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Hiroyuki Takahashi Selected Research

Intra-Arterial Injections

11/2021Suppression of Tumor Growth in a Rabbit Hepatic Cancer Model by Boron Neutron Capture Therapy With Liposomal Boron Delivery Systems.
9/2020Single-dose toxicity study by intra-arterial injection of 10BSH entrapped water-in-oil-in-water emulsion for boron neutron capture therapy to hepatocellular carcinoma.
6/2017Selective boron delivery by intra-arterial injection of BSH-WOW emulsion in hepatic cancer model for neutron capture therapy.
6/2014Pilot clinical study of boron neutron capture therapy for recurrent hepatic cancer involving the intra-arterial injection of a (10)BSH-containing WOW emulsion.
12/2011Feasibility evaluation of neutron capture therapy for hepatocellular carcinoma using selective enhancement of boron accumulation in tumour with intra-arterial administration of boron-entrapped water-in-oil-in-water emulsion.

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Hiroyuki Takahashi Research Topics

Disease

97Neoplasms (Cancer)
10/2022 - 02/2003
40Carcinoma (Carcinomatosis)
01/2022 - 08/2002
34Prostatic Neoplasms (Prostate Cancer)
03/2022 - 08/2003
29Carcinogenesis
01/2022 - 08/2002
25Neoplasm Metastasis (Metastasis)
08/2021 - 09/2005
14Lymphatic Metastasis
04/2013 - 10/2005
12Lymphoma (Lymphomas)
01/2021 - 10/2003
12Adenoma (Adenomas)
12/2014 - 10/2005
11Inflammation (Inflammations)
01/2021 - 09/2005
9Lung Neoplasms (Lung Cancer)
07/2022 - 09/2007
9Body Weight (Weight, Body)
01/2021 - 01/2013
9Leukemia
12/2020 - 10/2003
8Stomach Neoplasms (Stomach Cancer)
10/2022 - 09/2006
8Rheumatoid Arthritis
02/2022 - 02/2014
8Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
09/2019 - 10/2003
7Disease Progression
02/2022 - 10/2010
7Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2021 - 11/2013
7Immunoglobulin G4-Related Disease
01/2021 - 01/2015
7Adenocarcinoma
01/2021 - 10/2005
7Hepatocellular Carcinoma (Hepatoma)
01/2021 - 09/2006
7Fibrosis (Cirrhosis)
01/2021 - 03/2014
6Retinal Perforations
03/2022 - 01/2015
6Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 10/2005
6Infections
01/2020 - 05/2004
6Hyperplasia
01/2018 - 01/2013
5Retinal Detachment (Retinal Detachments)
01/2022 - 01/2015
5Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2021 - 09/2012
4Liver Neoplasms (Liver Cancer)
11/2021 - 05/2012
4Systemic Lupus Erythematosus (Libman-Sacks Disease)
11/2021 - 12/2020
4Type 2 Diabetes Mellitus (MODY)
10/2021 - 01/2015
4Colonic Neoplasms (Colon Cancer)
08/2017 - 10/2005
4Chromosome Aberrations (Chromosome Abnormalities)
01/2017 - 06/2004
3Respiratory Insufficiency (Respiratory Failure)
07/2022 - 12/2012
3Macular Degeneration (Age-Related Maculopathy)
05/2022 - 10/2019
3Myopia
05/2022 - 12/2018
3Urinary Bladder Neoplasms (Bladder Cancer)
03/2022 - 09/2019
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2022 - 01/2013
3Graft vs Host Disease (Graft-Versus-Host Disease)
12/2021 - 07/2006
3Hemorrhage
10/2021 - 09/2006
3Margins of Excision
10/2021 - 08/2009
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2021 - 01/2016
3Down Syndrome (Down's Syndrome)
01/2021 - 08/2012

Drug/Important Bio-Agent (IBA)

35Proteins (Proteins, Gene)FDA Link
09/2020 - 06/2004
18Messenger RNA (mRNA)IBA
01/2020 - 11/2003
12DNA (Deoxyribonucleic Acid)IBA
10/2020 - 09/2003
11Biological ProductsIBA
01/2022 - 02/2006
10AntibodiesIBA
12/2021 - 10/2005
9AndrogensIBA
01/2022 - 06/2009
9Rituximab (Mabthera)FDA Link
01/2020 - 04/2009
9SteroidsIBA
03/2019 - 04/2009
8Adrenal Cortex Hormones (Corticosteroids)IBA
07/2022 - 07/2015
8Biomarkers (Surrogate Marker)IBA
03/2022 - 06/2009
7Doxorubicin (Adriamycin)FDA LinkGeneric
01/2022 - 07/2011
7BoronIBA
11/2021 - 09/2007
7LigandsIBA
01/2021 - 05/2015
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2015 - 09/2005
6Pharmaceutical PreparationsIBA
06/2022 - 02/2012
6Indicators and Reagents (Reagents)IBA
01/2022 - 09/2006
6CateninsIBA
01/2022 - 01/2014
6Glucose (Dextrose)FDA LinkGeneric
08/2015 - 07/2008
5Abatacept (Orencia)FDA Link
02/2022 - 03/2015
5Retinaldehyde (Retinal)IBA
01/2022 - 01/2015
5Estrogen ReceptorsIBA
01/2022 - 06/2011
5Prednisolone (Predate)FDA LinkGeneric
12/2021 - 08/2008
5Cyclophosphamide (Cytoxan)FDA LinkGeneric
03/2021 - 03/2014
5EmulsionsIBA
01/2021 - 12/2011
5Interleukin-17 (Interleukin 17)IBA
09/2020 - 05/2015
4Proliferating Cell Nuclear Antigen (PCNA)IBA
01/2022 - 08/2005
43,4,5,3',4'-pentachlorobiphenylIBA
01/2022 - 08/2002
4GP 4 (GP4)IBA
01/2021 - 11/2019
4Immunoglobulin G (IgG)IBA
10/2020 - 01/2020
4Peptides (Polypeptides)IBA
09/2020 - 05/2015
4Insulin (Novolin)FDA Link
07/2019 - 01/2015
4Methotrexate (Mexate)FDA LinkGeneric
03/2019 - 12/2013
4Hormones (Hormone)IBA
01/2019 - 10/2010
4Cyclosporine (Ciclosporin)FDA LinkGeneric
07/2018 - 07/2006
4Prednisone (Sone)FDA LinkGeneric
03/2015 - 02/2012
4Dibutyl Phthalate (Butyl Phthalate)IBA
07/2014 - 01/2013
4RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
12/2012 - 01/2010
4TensinsIBA
10/2009 - 03/2007
3YHO-1701IBA
02/2022 - 05/2020
3Cyclin D1IBA
01/2022 - 06/2011
3Fluconazole (Zonal)FDA LinkGeneric
05/2021 - 11/2012
3STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2021 - 01/2010
3Estrogens (Estrogen)FDA Link
01/2021 - 01/2008
3CytokinesIBA
01/2021 - 01/2010

Therapy/Procedure

57Therapeutics
07/2022 - 07/2004
21Drug Therapy (Chemotherapy)
01/2022 - 04/2004
12Brachytherapy
02/2022 - 10/2005
11Radiotherapy
07/2022 - 03/2012
11Prostatectomy (Retropubic Prostatectomy)
03/2022 - 06/2009
7Boron Neutron Capture Therapy
11/2021 - 09/2007
6Hematopoietic Stem Cell Transplantation
12/2022 - 10/2013
5Intra-Arterial Injections
11/2021 - 12/2011
5Neutron Capture Therapy
06/2017 - 12/2011
4Traction
05/2022 - 05/2016
4Stem Cell Transplantation
12/2020 - 07/2006
4Vitrectomy
10/2020 - 08/2018
3Cystectomy
03/2022 - 07/2004
3Aftercare (After-Treatment)
02/2022 - 07/2013